Monday 23 May 2016

Hemophilia facts

  • Hemophilia is one of a group of inherited bleeding disorders that cause abnormal or exaggerated bleeding and poor blood clotting.
  • Hemophilia A and B are inherited in an X-linked recessive genetic pattern, so males are commonly affected while females are usually carriers of the disease.
  • Hemophilia A is caused by a deficiency of clotting Factor VIII, while hemophilia B (also called Christmas disease) results from a deficiency of Factor IX.
  • Hemophilia varies in its severity among affected individuals.
  • Symptoms include excessive bleeding from any site in the body; long-term damage to joints from repeated bleeding episodes is characteristic.
  • Treatment involves coagulation factor replacement therapy.
  • The formation of inhibitors to the treatment factor concentrates is a significant complication of treatment.
  • Gene therapy treatments are a source of active research and hold promise for the future.



source : http://www.medicinenet.com/hemophilia/article.htm

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